Naloxone is a safe and effective life-saving FDA-approved medication that is used to reverse the effects of an opioid overdose. Naloxone can support the restoration of normal breathing to a person if their breathing has slowed or stopped because of an opioid overdose. Naloxone has no effect on someone who does not have opioids in their system, and it is not a treatment for opioid use disorder. It is available in nasal or injectable forms and access varies by state. Community based naloxone distribution prioritizes populations at high risk of overdose, such as those in criminal justice systems.