Law enforcement and other first responders are on the front lines of addressing illicit substance use and misuse, responding to drug overdoses and other calls for service involving individuals with substance use, mental health, and co-occurring disorders. A variety of multidisciplinary law enforcement and first-responder models, or pathways, have emerged in communities throughout the nation that connect individuals to treatment services and recovery supports. These models often include first responders working in partnership with behavioral health treatment providers and peer recovery coaches to provide linkages to community-based treatment, services, and resources to support individuals in need.