The Naloxone Vending Machine Learning Collaborative (LC) was established in 2023 to bring together communities that had implemented, or were exploring the implementation of, vending machines for naloxone distribution. The LC provided an opportunity for attendees to learn best practices in facilitating the effective deployment of naloxone vending machines, such as identifying appropriate locations for naloxone vending machines, understanding the different types and features of the machines, methods of data collection, and managing operational logistics. This document provides answers to the most frequently asked questions raised during the LC series, and lessons learned.