This presentation covers the welcome by Ryan K. Buchanan and the opening plenary, Partnering Across State and Local Overdose Fatality Reviews. Together with national support, state and local health departments are identifying and implementing recommendations to prevent substance-related deaths in communities across the country. Many state agencies, in partnership with the Bureau of Justice Assistance’s Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) training and technical assistance provider, are building state-level infrastructure to support local overdose fatality reviews (OFRs). This session will highlight resources and tools available to partner across state and local OFRs.