The Federal Office of Rural Health Policy (FORHP) piloted a program in 2015 called the Rural Opioid Overdose Reversal (ROOR) Program that funded 18 awardees to develop community partnerships in an effort to combat the opioid crisis at the local level. The goal of the program was to reduce the incidences of morbidity and mortality related to opioid overdoses in rural communities through the purchase and placement of naloxone, in addition to the training of licensed healthcare professionals,emergency responders, and other community members to recognize the signs and symptoms of overdose and administer naloxone. This report provides a summary of lessons learned from ROOR grant recipients on how to engage, educate and connect stakeholders to resources available to help combat the opioid overdose epidemic. This report provides a summary of lessons learned from ROOR grant recipients on how to engage, educate, and connect stakeholders to resources available to help combat the opioid overdose epidemic.