This webinar showcases innovative best practices to mitigate the negative effects experienced by children exposed to trauma—including an arrest or incident related to opioid use—and highlights Handle With Care. This promising initiative partners schools and child-care agencies, law enforcement, and treatment providers to promote safe and supportive homes, schools, and communities with the goals of protecting children and helping traumatized children heal and thrive. When an officer encounters a child during a call, that child's name and three words—HANDLE WITH CARE—are forwarded before the school bell rings the next day. Schools respond with interventions to help mitigate the trauma, and mental health providers are being co-located at schools to provide services.