Between 2014 and 2019, South Carolina saw an increase in overdose deaths every year, with an additional 49 percent increase in opioid-related deaths statewide through September 2020. Lexington County (part of the Columbia metropolitan area), one of six High Intensity Drug Trafficking Area counties, mirrored this trend, with overdose deaths rising to 112 in 2020 compared to 65 in 2019. In 2020, emergency medical services (EMS) in the county administered Narcan, the lifesaving medication that reverses an opioid overdose, 264 times. To build the evidence base for an overdose prevention response, TCC secured a one-year implementation grant from the National Association of County and City Health Officials (NACCHO) and the Centers for Disease Control and Prevention’s Overdose Response Strategy.  Read about the successes and lessons learned of TCC's overdose prevention response in this success story, submitted by Pam Imm, Ph.D., Community Psychologist, Board Chairperson, The Courage Center.